Features of Information Provided

1. Cardiovascular Cartogram

  • Based on the patient’s body surface area, pressure variations etc.,a Predictive Kinetic model is first constructed.
  • Then the measured Data from the cardiac cycle is superimposed and mapped to obtain the Deviation Difference between the measured and predicted haemodynamics.
  • A CV-Cartogram is a special representation of this deviation difference, that gives a trained physician, an idea of the deviation difference and changes that may be  physiological, compensatory or pathological.
  • Thus CV-Cartogram is a relationship between the Pressure, Volume, Time, Contractility and flow. In short, the Cardiovascular Circulatory Status

2. Flow Turbulence

  • Flow turbulence, During Coronary filling provides the  3rd Dimension required for the Short Axis Slices (SAS) reconstruction.
  • SAS maps the exact origin of turbulence in three dimensions by associating and rendering with minute haemodynamic changes obtained by Kinetic Modeling in the CV-Cartography

3. Realistic Geometry Reconstruction

4. Reconstruction Of Effective Coronary Narrowing


  • From the SAS, the Culprit vessel supplying the regions are Identified
  • Effective Coronary Narrowing (ECN) is then calculated based on the regional Blood flow
  • Effective Coronary Narrowing is NOT the Anatomical “BLOCKADE” seen in Coronary Angiograms, but the NET CONTIBUTION OF THE CULPRIT VESSEL IN REDUCING THE FLOW IN THE REGION
     
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5. Vessels Contributing to Flow in various regions

6. Effective Coronary Narrowing

  • ECN is the net CONTRIBUTION by the epicardial vessels on the Reduced Myocardial Blood flow
  • ECN is the true Cardiac Physiological Effect, from an  Anatomical cause
  • Reduction in Myocardial Blood flow has more than 50 causes, Coronary artery disease is one of them and contributes to the extent of 70% of the problem
  • Cardiovascular Cartography is not just to measure regional myocardial blood flow, BUT to understand the patients cardiovascular physiology and aid in the TREATMENT to ensure better quality of Life.

7. Arterial Compliance


Normal Total Arterial Compliance

Impaired Arterial Compliance
  • Total Arterial Compliance is the ability of the Arteries to comply with the blood flowing through it by altering it’s elastic properties. The Elasticity of the Arterial system will diminish over the period of time and become Rigid. 
  • This Process is faster in some people, due to endothelial dysfunction - leading to Atherosclerosis. 
  • Arterial compliance can be used to detect Endothelial Dysfunction in Diabetes, Hypertension and Hyperlipidemia, etc.

8. Ventricular Compliance


Normal Ventricular Compliance

Impaired Ventricular Compliance
  • As the Ventricle fills with blood in time, the pressure and volume that results from filling are determined by the compliance of the ventricle. This is also sometimes referred to as Ventricular “Stiffness”. 
  • Ventricular Compliance  is given as millisecond/milliliters of filled volume/mmHg change in pressure. Besides Hypertrophy, Ventricular Compliance is impaired in some forms of Heart Failure and  Impaired Glucose Tolerance or Uncontrolled Diabetes.
     
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9. Adrenergic State


Normal Adrenergic State

Hyper Adrenergic Activity
  • Complex Analysis of Intra-Cycle Systolic Timings are the only method to estimate the Adrenergic State at any moment in the Clinical setting.

10. Predominance of Autonomic Nervous System

  • ANS Predominance is an excellent Indicator of Forced cardiac activity.
  • Predominantly Sympathetic Subjects are prone to Cardiac anomalies including Cardiac Sudden Death Syndrome. Sympathetic Overdrive is an Indicator of poor prognosis.
  • Predominance of Autonomic Nervous System can be used to understand ans-activity and treat patients accordingly.

11. Pressure Volume Loop

            PV-Loop showing early                                           PV-Loop indicating normal                             PV-Loop showing early
            Diastolic Dysfunction                                                 filling and ejection                                             Systolic Dysfunction

  • PV-Loop needs no explanations, Every Medical Student knows about it. - Now they should know that it is possible Non-Invasively.
  • Pressure Volume Loop is the most sensitive method to assess overall cardiac function and identify early changes.

12. Inter Cycle Electrophysiology

  • Early and Delayed After Depolarisation are substrates for Arrhythmogenicity. Cardiovascular Cartography is the only method by which the presence of EAD and DAD can be detected. 
  • Arrhythmogenicity is a major cardiac problem, leading to cardiac suddent death, know the arrhythmogenic status of your patients before prescribing, as certain drugs also trigger arrhythmia in arrhythmia prone patients.

13. Myocardial Demand and Supply

                                     Normal Demand                               Decompensated Demand                     Demand During Infraction

  • Myocardial Demand, Supply and Reserve is the best indicator of Cardiac Ischemia 
  • Myocardial Demand, Supply and Reserve - at rest, reactive Hypermia or stress is importaint in modern patient management.
     
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14. Thrombus Formation Factor


Normal TFF

Elevated TFF

  • Thrombus Formation Factor (TFF) Indicates the Thrombogenicity. It is well known that the Turbulence and blood viscosity plays an Important role in thrombus formation. TFF enables to handle thromogenic patients with care.

15. Effect of Hypertension - Hypertrophy


Hypertension under good control

Hypertension under bad control

  • Complex Analysis of Intra-Cycle Timings can NOW be used to assess the net effect of long term hypertension. Aids in the perfect management of  hypertension

16. Ventricular Relaxibility


                                                       Patient with PROLONGED                                Patient with SHORTENED 
                                                        V entricular Relaxibility                                       Ventricular Relaxibility
  • Ventricular Relaxibility is a good method to assess patients with Thyroid Dysfunction. 

17. Total Myocardial Burden


Patient with NO Myocardial Burden

Patient with HIGH Myocardial Burden

  • Total Myocardial Burden is the net mechanical strain imposed on the myocardium, and  is important in determining patient’s exertion tolerance specially during Post MI and Rehabilitation

18. Valve Insufficiency and Orifice Area


Patient with NORMAL Aortic Orifice Area

Patient with REDUCED Aortic Orifice Area

  • 3D CCG Calculates Valve orifice area using Gorlin Formula. Early detection of Valvular Insufficiencies are a boon to Patients with Valvular Heart Disease.

Mitral Stenosis - Pre Valvoplasty

Mitral Stenosis - Post Valvoplasty

  • 3D CCG Calculates Valve orifice area using Gorlin Formula. Early detection of Valvular Insufficiencies are a boon to Patients with Valvular Heart Disease.
     
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